ecotips-gentech
ecotips-gentech

ECO-Tips

Eco – Tips, the technical-environmental line of the ECO-GENTECH corporate program, whose main objective is to improve researchers’ knowledge of the characteristics of the different plastic ware used in the laboratory, facilitating decision-making on the technical characteristics of plastic inputs and their suitability for each process, improving efficiency and reducing the loss of reagents

Line's objectives

Gentech Biosciences, understand the connection between research activities and laboratory practices with the health of the planet and the impact of improper waste use and disposal. Every day we work to promote corporate strategies and to improve processes and routine methods that enhance sustainable practices in our processes and those of our customers. Every day we work to promote corporate strategies and improvements in processes and routine methods that enhance sustainable practices in our processes and those of our customers.

As a company committed with the environmental sustainability, articulated with the Sustainable Development Goals – SDGs, our environmental program ECO – GENTECH is constructed and structured, as a corporate strategy that seeks to make us, as a company aware of minimizing the negative footprint of our activities over the environment and to be better administrators of the environment.

GREEN-LAB-METRICS
GREEN-LAB-METRICS

Green Lab Metrics 4.0

GreenLab Metrics 4.0 is a line of ECO-GENTECH that integrally to the processes of accreditation and Good Laboratory Practices (GLP), seeks to ensure that laboratory practices are performed in a way that guarantees biosafety in the internal and external environment of the laboratory, as well as economic and environmental sustainability.

Line's objectives

GreenLab Metrics 4.0, is an ECO-GENTECH initiative that integrates the processes of accreditation and Good Laboratory Practices (GLP) with International requirements. It seeks to ensure that practices in research and service laboratories are carried out in a way that guarantees biosafety in the internal and external environment of the laboratory, as well as economic and environmental sustainability.

The program seeks to strengthen knowledge and practices in laboratories that minimize, eliminate or even reverse negative environmental impact, improving (substitution of toxic chemicals) and simplifying procedures (smaller or micro scale), optimizing flow charts/spaces and assessing energy consumption and saving strategies to improve efficiency in the use of energy and determine the level or degree of technological updating requirements by laboratory area.

Mitochondrial Whole genome re-sequencing(Mitochondrial Genome)

Mitochondrial Whole genome re-sequencing

The mitochondrial genome contains a total of 37 genes of which 13 genes codify for messenger RNAs, and as a consequence for 13 proteins, 22 genes codify for 22 tRNAs (transfer RNAs) and 2 genes codify for two mitochondrial rRNAs (ribosomal RNAs). In practice, when sequencing the myocrondrial DNA of a particular person, a number of variations are observed that are simply polymorphisms of no clinical consequence. In fact, one region of the mitochondrial DNA, called the control region, is so polymorphic that it is used in forensic medicine to identify the subject.

In humansmutations in some of the mitochondrial genes cause diseases, thus the relevance and application of sequencing of these cellular organelles.

The mitochondrial DNA or genome (mitogenome) generally has maternal inheritance, low recombination rate and high evolutionary rates, so it is widely used as a phylogenetic marker to resolve evolutionary relationships at different taxonomic levels.

mitochondrial

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Metagenome Sequencing

Metagenome Sequencing

Metagenome sequencing is a method for identifying microbial communities in different environments. It is primarily used to analyze the distribution and types of bacteria and fungi. It is used to determine which microbial community complexes are present in a sample collected in a given environment and to identify their interactions and roles.

Shotgun Metagenome Sequencing

Shotgun Metagenome Sequencing

Shotgun metagenomic sequencing is a method of complete sampling of the genes in the organism present in a composite sample. This method is capable of assessing microbial diversity and determining species abundance under different conditions.

Shotgun metagenomic sequencing provides information on what organisms are present and what metabolic processes take place in the microbial community.

shotgun-metagenome-sequencing

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Metagenome Sequencing

Metagenome Sequencing

Metagenome sequencing is a method for identifying microbial communities in different environments. It is primarily used to analyze the distribution and types of bacteria and fungi. It is used to determine which microbial community complexes are present in a sample collected in a given environment and to identify their interactions and roles.

Amplicon Metagenome Sequencing

Amplicon Metagenome Sequencing

Metagenomic sequencing of amplicons allows efficient identification of the diversity of microorganisms in a specific environment by sequencing genomespecific regions of microorganisms.

amplicon

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Transcriptome sequencing and analysis (eukaryotic and prokaryotic organisms)

Whole Transcriptome Sequencing

Transcriptome sequencing by next generation sequencing (NGS) is a fast and reliable method to identify genomic information. Gentech provides whole RNA transcriptome expression services, enabling the discovery of new genes, identification of new SNPs and InDel, discovery of new splice variants and chromosomal rearrangements, identification of fusion genes, and determination of differential gene expression.

Transcriptome sequencing, which targets RNA, is one of the most widely used research methods. When studying a living organism without reference genome information, transcriptome analysis of the living organism is possible by de novo assembly. The difference in gene expression values (expression profile) can be verified by transcriptome analysis.

Whole-Transcriptome-Sequencing​

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Whole genome sequencing

Whole Genome Sequencing (WGS)

Sequencing
de novo

De Novo Sequencing De novo sequencing is typically performed when there is no prior knowledge of an organism’s sequencing data. Sequencing De novosequencing has proven effective in confirming an extension of results from database searches, providing excellent resources for understanding a species

Genome Re-sequencing

Some of the most important information obtained by DNA resequencing of an organism’s genome is individual variation in the genome, such as single nucleotide polymorphism (SNP), copy number variation (CNV) and structural variation (SV).

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Line's Name (*) Genetic engineering, microbiological diagnosis and applied molecular biology.
Line Objectives Incorporate latest methodologies in molecular diagnostics and the development of products and services for microbiological diagnostics as a strategy for strengthening the technical-business and scientific capabilities of universities and Technology Development Centers (TDCs) in the region and the country.
Achievments of the line * Consolidation of a reference laboratory for molecular diagnostics with high quality standards.
* Standardization of state-of-the-art techniques for the accurate, fast and accurate identification of the largest possible number of microorganisms for diagnostic applications, water quality certification, food and product safety and traceability, and other environmental monitoring services.
Effects of the line Increasing the availability of certified molecular diagnostic products and services in the regional and national market, and becoming leaders in the service of fast diagnostic tests to human, animal and plant health.
Line's Name (*) Bio-prospecting of compounds of medical and cosmetic importance
Line Objectives Generate solutions and direct applications from the identification, characterization and use of bioactive compounds to meet the demands of different sectors, especially the pharmaceutical and cosmetic, through basic and applied research with a direct translation into the development and improvement of services, processes and products.
Achievments of the line Strengthening the scientific capabilities of professionals and researchers in the area of bioprospecting and application of biological compounds to different sectors, so that they can contribute to the generation of solutions to problems in the different productive sectors of the country.
Effects of the line Increase in offer of trained researchers with high capacity for management, innovation and problem resolution from the application of bio-prospecting and state-of-the-art diagnostics.
Line's Name (*) Transdisciplinary research
Line Objectives Make strategic partnerships between the GENTECH Biosciences Research Group, and the Applied BioCenter for Development and Innovation with the pharmaceutical, industrial, agricultural and environmental sectors, to generate solutions and direct applications to satisfy the demands of the different sectors and satisfy other requirements that can be addressed through basic and applied research with a direct impact on the development of services, processes and products.

To integrate GENTECH Biosciences with different academic programs of Universities in the region, around topics of joint interest, for transdisciplinary research applied to different sectors of regional importance.
Achievments of the line Constant management of integration with private companies for the application of bio-prospecting of compounds of medicinal and cosmetic importance, microbiological and molecular diagnostics, and solutions to specific problems generated in the development of services, processes and products.

Permanent technological vigilance to prioritize research topics as well as the transfer of appropriate technologies for the application of bio-prospecting of compounds of medicinal and cosmetological importance, as well as for the diagnosis of quality and safety of processes and products.
Effects of the line Positioning of the research group GENTECH Biosciences as a leading and reference in the management and execution of research activities that integrates private companies and different productive sectors for the development of services, processes and products in compliance with the GENTECH Biosciences vision.
2019-2036, The group seeks to be a promoter of the development of the region and the country through a continuous adaptation to the environment and the achievement of high quality standards in its substantive functions.

Support the transfer of knowledge and developments from/to the company, academia and productive sectors, and to contribute to one of the main objectives of GENTECH Biosciences research group "Promote the training of high-level researchers to help to the improvement of R+D+I indicators of the region and the country".
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